A Randomized, Controlled Trial of Magnesium Sulfate for the Prevention of Cerebral Palsy
نویسندگان
چکیده
Dwight J. Rouse, M.D., Deborah G. Hirtz, M.D., Elizabeth Thom, Ph.D., Michael W. Varner, M.D., Catherine Y. Spong, M.D., Brian M. Mercer, M.D., Jay D. Iams, M.D., Ronald J. Wapner, M.D., Yoram Sorokin, M.D., James M. Alexander, M.D., Margaret Harper, M.D., John M. Thorp, Jr., M.D., Susan M. Ramin, M.D., Fergal D. Malone, M.D., Marshall Carpenter, M.D., Menachem Miodovnik, M.D., Atef Moawad, M.D., Mary J. O’Sullivan, M.D., Alan M. Peaceman, M.D., Gary D.V. Hankins, M.D., Oded Langer, M.D., Steve N. Caritis, M.D., and James M. Roberts, M.D., for the Eunice Kennedy Shriver NICHD Maternal–Fetal Medicine Units Network*
منابع مشابه
Training Mothers to Improve Gross Motor Skills in Children With Cerebral Palsy: A Randomized Controlled Trial
Objectives: The present study examined the effect of home-based handling training of mothers on the improvement of gross motor function of children with Cerebral Palsy (CP). Methods: In this randomized control trial, 42 children with CP (5-12 years old) were randomly assigned into the intervention and control groups. Data were collected using the Gross Motor Function Classification System and ...
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Preterm infants are at increased risk for serious, lifelong neurologic abnormalities such as cerebral palsy.1,2 As the survival of preterm infants has improved with advances in perinatal care,2 the occurrence of cerebral palsy has increased further, since infants who would previously have died now survive with their cerebral pathology. Currently, more than 30% of children with cerebral palsy ar...
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CONTEXT Prenatal magnesium sulfate may reduce the risk of cerebral palsy or death in very preterm infants. OBJECTIVE To determine the effectiveness of magnesium sulfate given for neuroprotection to women at risk of preterm birth before 30 weeks' gestation in preventing pediatric mortality and cerebral palsy. DESIGN, SETTING, AND PATIENTS Randomized controlled trial at 16 tertiary hospitals ...
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At the present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. Although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but its optimal use has yet to be delineated. In this study a high-dose protocol for magnesium sulfate tocolytic therapy was compared with a low-dose regimen. One-hundred patie...
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OBJECTIVE To review the evidence regarding neuroprotective effects of antenatal exposure to magnesium sulfate. DATA SOURCES We conducted database searches of MEDLINE, the Cochrane Library and Controlled Trials Register, as well as the ClinicalTrials.gov and International Clinical Trials Register websites. Bibliographies of all relevant articles were reviewed. METHODS OF STUDY SELECTION Rand...
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